BDBM153265 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-3-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxychromen-4-one::Isoquercitrin (6)::Quercetin 3-O-β-D-glucoside (11)

SMILES c1cc(c(cc1C2=C(C(=O)c3c(cc(cc3O2)O)O)O[C@H]4[C@@H]([C@H]([C@@H]([C@H](O4)CO)O)O)O)O)O

InChI Key InChIKey=OVSQVDMCBVZWGM-UHFFFAOYSA-N

Data  3 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 153265   

TargetAurora kinase B(Human)
Konkuk University

LigandPNGBDBM153265(2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-3-[(2S,3R,4S...)
Affinity DataIC50: 1.07E+4nMAssay Description:The kinase assay was performed using the EMD Millipore KinaseProfiler service assay protocol. Aurora B kinase was supplied by EMD Millipore Corp. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2015
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Catholic University of Daegu

LigandPNGBDBM153265(2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-3-[(2S,3R,4S...)
Affinity DataIC50: 1.00E+5nMpH: 6.0Assay Description:PTP1B activity was measured by adding 2mM p-NPP and PTP1B in a 50 mM citrate buffer (pH 6.0, 0.1 M NaCl, 1 mMEDTA, and 1 mM dithiothreitol), with or ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2017
Entry Details

TargetAcetylcholinesterase(Human)
Catholic University of Daegu

LigandPNGBDBM153265(2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-3-[(2S,3R,4S...)
Affinity DataIC50: 8.48E+4nMpH: 8.0 T: 2°CAssay Description:Briefly, 140 μL of sodium phosphate buffer (pH 8.0), 20 μL of each tested compound with different concentrations (4, 20, and 100 μM) a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2017
Entry Details