BDBM153236 US8993756, 33-3

SMILES COc1ccc(F)cc1-c1c[nH]c2ncnc(-c3ccccc3)c12

InChI Key InChIKey=BCNPPSRRHIVGRC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 153236   

TargetTyrosine-protein kinase JAK3(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM153236(US8993756, 33-3)
Affinity DataIC50: 1.40nMT: 2°CAssay Description:The ability of compounds to inhibit the activity of JAKl, JAK2, JAK3, and Tyk2 was measured using a recombinant purified GST-tagged catalytic domain ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2015
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM153236(US8993756, 33-3)
Affinity DataIC50: 71nMT: 2°CAssay Description:The ability of compounds to inhibit the activity of JAKl, JAK2, JAK3, and Tyk2 was measured using a recombinant purified GST-tagged catalytic domain ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2015
Entry Details
US Patent