BDBM152800 1-(2-(4-(7-Chloro-4-quinolyl)piperazin-1-yl)acetyl)pyrrolidine (2g)

SMILES Clc1ccc2c(ccnc2c1)N1CCN(CC(=O)N2CCCC2)CC1

InChI Key InChIKey=OBBLGGTVVLXSCX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 152800   

TargetDipeptidyl peptidase 4(Human)
Csir-Central Drug Research Institute

LigandPNGBDBM152800(1-(2-(4-(7-Chloro-4-quinolyl)piperazin-1-yl)acetyl...)
Affinity DataIC50: 3.73E+3nMAssay Description:DPP-IV inhibitory activity was determined by measuring the p-nitroaniline (pNA) released from the chromogenic substrate hydrolysis (H-Gly-Pro-pNA). T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2015
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Csir-Central Drug Research Institute

LigandPNGBDBM152800(1-(2-(4-(7-Chloro-4-quinolyl)piperazin-1-yl)acetyl...)
Affinity DataIC50: 3.73E+3nMAssay Description:Inhibition of recombinant human DPP4 assessed as hydrolyzing H-Gly-Pro-pNA hydrolysis by measuring p-nitroaniline release after 10 mins by double bea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed