BDBM152740 5-(4-chlorophenyl)benzo[c]2,6-naphthyridine-8-carbonitrile (Compound 10)

SMILES Clc1ccc(cc1)-c1nc2cc(ccc2c2cnccc12)C#N

InChI Key InChIKey=RGYUSOFVBUIIIT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 152740   

TargetCasein kinase II subunit alpha [1-337](Human)
Beijing University of Technology

LigandPNGBDBM152740(5-(4-chlorophenyl)benzo[c]2,6-naphthyridine-8-carb...)
Affinity DataIC50: 2.50E+3nMAssay Description:The atomic co-ordinates of CK2α were retrieved from the Protein Data Bank [PDB ID: 3PE1] by deleting the heteroatoms except for water molecules ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2015
Entry Details Article
PubMed
TargetCasein kinase II subunit alpha'/beta(Human)
Cylene Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM152740(5-(4-chlorophenyl)benzo[c]2,6-naphthyridine-8-carb...)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of human recombinant CK2alpha/CK2beta using RRRDDDSDDD peptide as substrate by radiometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed