BDBM152604 1-[4-(2,6-dimethylphenyl)but-1-en-2-yl]-3,5-dimethyladamantane (5)

SMILES CC12CC3CC(C)(C1)CC(C3)(C2)C(=C)NNc1c(Cl)cncc1Cl

InChI Key

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 152604   

TargetP2X purinoceptor 7(Human)
Gwangju Institute of Science and Technology

LigandPNGBDBM152604(1-[4-(2,6-dimethylphenyl)but-1-en-2-yl]-3,5-dimeth...)
Affinity DataIC50: 13nMpH: 7.4Assay Description:hP2X7-expressing HEK 293 cells were re-suspended at 2.5 × 10^6 cells/mL in assay buffer composed of 10 mM HEPES, 5 mM N-methyl-D-glutamine, 5.6 mM KC...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2015
Entry Details Article
PubMed