BDBM152557 7,8-dimethoxy-5-((1-(2-nitrophenylsulfonyl)piperidin-4-ylamino)methyl)-1H-benzo[e]isoindole-1,3(2H)-dione (8f)

SMILES COc1cc2c3C(=O)NC(=O)c3cc(CNC3CCN(CC3)S(=O)(=O)c3ccccc3[N+]([O-])=O)c2cc1OC

InChI Key InChIKey=SAHQTJMMXXCVDX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 152557   

TargetGlycogen synthase kinase-3 beta(Human)
Peking University

LigandPNGBDBM152557(7,8-dimethoxy-5-((1-(2-nitrophenylsulfonyl)piperid...)
Affinity DataIC50: 530nMpH: 7.4Assay Description:Briefly, recombinant human GSK3β (1 µM, 10 µL) was mixed with 10 µL of GSK3β substrate (YRRAAVPPSPSLSRHSSPHQpSEDEEE, 100 µM), 19 µL of 2.5 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2015
Entry Details Article
PubMed