BDBM152461 1-(4-Bromophenyl)-3-(4-(8-methoxy-2-oxo-2H-chromen-3-yl)thiazol-2-yl)urea (e25)

SMILES COc1cccc2cc(-c3csc(NC(=O)Nc4ccc(Br)cc4)n3)c(=O)oc12

InChI Key InChIKey=MUAFOYUPEDFXAE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 152461   

TargetAcetylcholinesterase(Electric eel)
Bezmialem Vakif University

LigandPNGBDBM152461(1-(4-Bromophenyl)-3-(4-(8-methoxy-2-oxo-2H-chromen...)
Affinity DataIC50: 6.91E+4nMpH: 8.0Assay Description:The substrates of the reaction were acetylthiocholine iodide and butyrylthiocholine iodide. 5,5'-dithio-bis(2-nitrobenzoic) acid (DTNB) was used ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2015
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Horse)
Bezmialem Vakif University

LigandPNGBDBM152461(1-(4-Bromophenyl)-3-(4-(8-methoxy-2-oxo-2H-chromen...)
Affinity DataIC50: 1.17E+5nMpH: 8.0Assay Description:The substrates of the reaction were acetylthiocholine iodide and butyrylthiocholine iodide. 5,5'-dithio-bis(2-nitrobenzoic) acid (DTNB) was used ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2015
Entry Details Article
PubMed