BDBM152457 1-(3-Fluorophenyl)-3-(4-(8-methoxy-2-oxo-2H-chromen-3-yl)thiazol-2-yl)urea (e21)

SMILES COc1cccc2cc(-c3csc(NC(=O)Nc4cccc(F)c4)n3)c(=O)oc12

InChI Key InChIKey=PTWXHCRNJYIGEK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 152457   

TargetAcetylcholinesterase(Electric eel)
Bezmialem Vakif University

LigandPNGBDBM152457(1-(3-Fluorophenyl)-3-(4-(8-methoxy-2-oxo-2H-chrome...)
Affinity DataIC50: 6.70E+4nMpH: 8.0Assay Description:The substrates of the reaction were acetylthiocholine iodide and butyrylthiocholine iodide. 5,5'-dithio-bis(2-nitrobenzoic) acid (DTNB) was used ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2015
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Horse)
Bezmialem Vakif University

LigandPNGBDBM152457(1-(3-Fluorophenyl)-3-(4-(8-methoxy-2-oxo-2H-chrome...)
Affinity DataIC50: 1.10E+5nMpH: 8.0Assay Description:The substrates of the reaction were acetylthiocholine iodide and butyrylthiocholine iodide. 5,5'-dithio-bis(2-nitrobenzoic) acid (DTNB) was used ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2015
Entry Details Article
PubMed