BDBM152455 1-(4-(8-Methoxy-2-oxo-2H-chromen-3-yl)thiazol-2-yl)-3-(4-nitrophenyl)urea (e19)

SMILES COc1cccc2cc(-c3csc(NC(=O)Nc4ccc(cc4)[N+]([O-])=O)n3)c(=O)oc12

InChI Key InChIKey=QLRWZNZAMHTFAQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 152455   

TargetAcetylcholinesterase(Electric eel)
Bezmialem Vakif University

LigandPNGBDBM152455(1-(4-(8-Methoxy-2-oxo-2H-chromen-3-yl)thiazol-2-yl...)
Affinity DataIC50: 4.65E+4nMpH: 8.0Assay Description:The substrates of the reaction were acetylthiocholine iodide and butyrylthiocholine iodide. 5,5'-dithio-bis(2-nitrobenzoic) acid (DTNB) was used ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2015
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Horse)
Bezmialem Vakif University

LigandPNGBDBM152455(1-(4-(8-Methoxy-2-oxo-2H-chromen-3-yl)thiazol-2-yl...)
Affinity DataIC50: 8.37E+4nMpH: 8.0Assay Description:The substrates of the reaction were acetylthiocholine iodide and butyrylthiocholine iodide. 5,5'-dithio-bis(2-nitrobenzoic) acid (DTNB) was used ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2015
Entry Details Article
PubMed