BDBM152340 US8993565, 59

SMILES COc1c(F)ccc(NC(=O)Cc2nc(cc(=O)[nH]2)N2CCOCC2)c1F

InChI Key InChIKey=NUWAGCLTVYNCLK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 152340   

TargetRAC-alpha serine/threonine-protein kinase(Human)
Sanofi

US Patent
LigandPNGBDBM152340(US8993565, 59)
Affinity DataIC50: 417nMT: 2°CAssay Description:This test is based on measuring the expression of the AKT protein phosphorylated on serine 473. The phosphorylation of AKT (pAKT) is measured by west...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2015
Entry Details
Go to US Patent

TargetRAC-alpha serine/threonine-protein kinase(Human)
Sanofi

US Patent
LigandPNGBDBM152340(US8993565, 59)
Affinity DataIC50: 50nMAssay Description:This test is based on measuring the expression of the AKT protein phosphorylated on serine 473 (P-AKT-S473), in the PC3 human prostate carcinoma line...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2015
Entry Details
Go to US Patent