BDBM152167 BDBM152170::US8987474, HL2-070-5

SMILES OC(=O)c1cccc(N\N=C2/C(=O)Nc3ccc(cc23)C(=O)NCc2ccc(Cl)cc2)c1

InChI Key InChIKey=SFONGWMOKJNSOO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 152167   

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
University of South Florida

US Patent
LigandPNGBDBM152167(BDBM152170 | US8987474, HL2-070-5)
Affinity DataIC50: 2.17E+4nMAssay Description:NSC-87877 ranked among top 10% (175th) of the compounds with the best GLIDE scores for the docking to the human Shp2 PTP domain in our virtual screen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2015
Entry Details
Go to US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
University of South Florida

US Patent
LigandPNGBDBM152167(BDBM152170 | US8987474, HL2-070-5)
Affinity DataIC50: 1.00E+5nMAssay Description:NSC-87877 ranked among top 10% (175th) of the compounds with the best GLIDE scores for the docking to the human Shp2 PTP domain in our virtual screen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2015
Entry Details
Go to US Patent