BDBM151583 US8987315, 3

SMILES COc1cc2ccc(cc2cc1OC)C(C(C)C)n1ncnn1

InChI Key InChIKey=DZBCCEIMLOAXBO-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 151583   

TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
Innocrin Pharmaceuticals

US Patent
LigandPNGBDBM151583(US8987315, 3)
Affinity DataIC50: 270nMAssay Description:Solutions of each test compound were separately prepared at concentrations of 20000, 6000, 2000, 600, 200, and 60 uM by serial dilution with DMSO:MeC...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2015
Entry Details
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TargetCytochrome P450 2C9(Human)
Innocrin Pharmaceuticals

US Patent
LigandPNGBDBM151583(US8987315, 3)
Affinity DataIC50: 4.80E+3nMAssay Description:Solutions of each test compound were separately prepared at concentrations of 20000, 6000, 2000, 600, 200, and 60 uM by serial dilution with DMSO:MeC...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2015
Entry Details
Go to US Patent

TargetCytochrome P450 2C19(Human)
Innocrin Pharmaceuticals

US Patent
LigandPNGBDBM151583(US8987315, 3)
Affinity DataIC50: 3.00E+4nMAssay Description:Solutions of each test compound were separately prepared at concentrations of 20000, 6000, 2000, 600, 200, and 60 uM by serial dilution with DMSO:MeC...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2015
Entry Details
Go to US Patent

TargetCytochrome P450 3A4(Human)
Innocrin Pharmaceuticals

US Patent
LigandPNGBDBM151583(US8987315, 3)
Affinity DataIC50: 2.00E+5nMAssay Description:Solutions of each test compound were separately prepared at concentrations of 20000, 6000, 2000, 600, 200, and 60 uM by serial dilution with DMSO:MeC...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2015
Entry Details
Go to US Patent