BDBM151469 US8987314, B280

SMILES CC(C)S(=O)(=O)C(C(=O)NCCS(N)(=O)=O)c1nc2c(F)cc(cc2s1)-c1cccc(c1)C(=O)OC(C)(C)C

InChI Key InChIKey=BMQWCACNEMPCGT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 151469   

TargetEndothelial lipase(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM151469(US8987314, B280)
Affinity DataIC50: 4.80nMpH: 8.0 T: 2°CAssay Description:Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2015
Entry Details
Go to US Patent

TargetHepatic triacylglycerol lipase(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM151469(US8987314, B280)
Affinity DataIC50: 2.90nMpH: 8.0 T: 2°CAssay Description:Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2015
Entry Details
Go to US Patent