BDBM151299 BDBM151558::US8987314, B95

SMILES CS(=O)(=O)C(C(=O)NCCS(N)(=O)=O)c1nc2cc(ccc2s1)-c1ccnc(F)c1

InChI Key InChIKey=HMXSAQYEGHMUAZ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 151299   

TargetEndothelial lipase(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM151299(BDBM151558 | US8987314, B95)
Affinity DataIC50: 10nMpH: 8.0 T: 2°CAssay Description:Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2015
Entry Details
Go to US Patent

TargetEndothelial lipase(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM151299(BDBM151558 | US8987314, B95)
Affinity DataIC50: 1.5nMpH: 8.0 T: 2°CAssay Description:Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2015
Entry Details
Go to US Patent

TargetHepatic triacylglycerol lipase(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM151299(BDBM151558 | US8987314, B95)
Affinity DataIC50: 70nMpH: 8.0 T: 2°CAssay Description:Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2015
Entry Details
Go to US Patent

TargetHepatic triacylglycerol lipase(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM151299(BDBM151558 | US8987314, B95)
Affinity DataIC50: 415nMpH: 8.0 T: 2°CAssay Description:Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2015
Entry Details
Go to US Patent