BDBM151198 US8987313, 49

SMILES CC(C)c1nc(CN(C)C(=O)N2Cc3nc[nH]c3C[C@H]2C(=O)N[C@H](CC[C@H](Cc2ccccc2)NC(=O)OCc2cncs2)Cc2ccccc2)cs1

InChI Key InChIKey=YUTMPZJGRVRLLE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 151198   

TargetCytochrome P450 3A4(Human)
Gilead Sciences

US Patent
LigandPNGBDBM151198(US8987313, 49)
Affinity DataIC50: 190nMT: 2°CAssay Description:The potencies of the compounds as inhibitors of human hepatic cytochromes P450 of the CYP3A subfamily (particularly CYP3A4) were assessed using well-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2015
Entry Details
Go to US Patent

TargetCytochrome P450 3A4(Human)
Gilead Sciences

US Patent
LigandPNGBDBM151198(US8987313, 49)
Affinity DataIC50: 370nMT: 2°CAssay Description:The potencies of the compounds as inhibitors of human hepatic cytochromes P450 of the CYP3A subfamily (particularly CYP3A4) were assessed using well-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2015
Entry Details
Go to US Patent