BDBM151176 US8987287, 6

SMILES COc1ccc2C[C@@H]3[C@@H]4CC[C@@]5(C[C@]4(CCN3CC3CC3)c2c1)NC(=O)NC5=O

InChI Key InChIKey=LDWIYLKXIXKTJM-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 151176   

TargetKappa-type opioid receptor(Human)
Purdue Pharma

US Patent
LigandPNGBDBM151176(US8987287, 6)
Affinity DataKi:  12.3nM ΔG°:  -10.8kcal/molepH: 7.4 T: 2°CAssay Description:Radioligand dose displacement assays used 0.4 nM [3H]-U69,593 (GE Healthcare, Piscataway, N.J.; 40 Ci/mmole) with 15 ug membrane protein (recombinant...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2015
Entry Details
Go to US Patent