BDBM151095 US8987273, 4-2

SMILES COC(=O)c1cccc(c1)-c1cnc2cc(-c3ccccc3)c(nn12)-c1ccc(cc1)C1(N)CCC1

InChI Key InChIKey=GKQGZDHOZXJUMQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 151095   

TargetRAC-alpha serine/threonine-protein kinase(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM151095(US8987273, 4-2)
Affinity DataIC50: 4nMpH: 7.5 T: 2°CAssay Description:Akt1 inhibitory activity of compounds of the present invention was quantified employing the Akt1 TR-FRET assay as described in the following paragrap...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2015
Entry Details
Go to US Patent

TargetRAC-beta serine/threonine-protein kinase(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM151095(US8987273, 4-2)
Affinity DataIC50: 58nMpH: 7.5 T: 2°CAssay Description:Akt2 inhibitory activity of compounds of the present invention was quantified employing the Akt2 TR-FRET assay as described in the following paragrap...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2015
Entry Details
Go to US Patent