BDBM151053 US8987268, 122

SMILES CC1(C)CN(CC[C@H]1Nc1c(cnn2cc(cc12)N1CCC(CCCC([O-])=O)C1=O)C(N)=O)c1ncc(cn1)C#N

InChI Key InChIKey=KQTMBQOVTYUNAC-UHFFFAOYSA-M

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 151053   

TargetTyrosine-protein kinase JAK3(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM151053(US8987268, 122)
Affinity DataIC50: 1.40nMpH: 7.4 T: 2°CAssay Description:The assay reactions were performed in U-bottom 384-well plates. The final assay volume was 30 ul prepared from 15 ul additions of enzyme and substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2015
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK1(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM151053(US8987268, 122)
Affinity DataIC50: 2.40nMpH: 7.4 T: 2°CAssay Description:The assay reactions were performed in U-bottom 384-well plates. The final assay volume was 30 ul prepared from 15 ul additions of enzyme and substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2015
Entry Details
Go to US Patent