BDBM151050 US8987268, 97

SMILES CCC(=O)N1C[C@H]2C[C@@H](Nc3c(cnn4cc(cc34)-c3ccc(F)nc3)C(N)=O)[C@H](C)[C@H]2C1

InChI Key InChIKey=GOGAPLINTFESOO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 151050   

TargetTyrosine-protein kinase JAK3(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM151050(US8987268, 97)
Affinity DataIC50: 1.40nMpH: 7.4 T: 2°CAssay Description:The assay reactions were performed in U-bottom 384-well plates. The final assay volume was 30 ul prepared from 15 ul additions of enzyme and substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2015
Entry Details
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TargetTyrosine-protein kinase JAK1(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM151050(US8987268, 97)
Affinity DataIC50: 3.10nMpH: 7.4 T: 2°CAssay Description:The assay reactions were performed in U-bottom 384-well plates. The final assay volume was 30 ul prepared from 15 ul additions of enzyme and substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2015
Entry Details
Go to US Patent