BDBM15058 N-(3-{5-[(2S)-2-amino-3-(1H-indol-3-yl)propoxy]pyridin-3-yl}phenyl)pyrimidin-2-amine::pyridine-base inhibitor 9u

SMILES N[C@H](COc1cncc(c1)-c1cccc(Nc2ncccn2)c1)Cc1c[nH]c2ccccc12

InChI Key InChIKey=FVTWTVHLHUNJHF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 15058   

LigandPNGBDBM15058(N-(3-{5-[(2S)-2-amino-3-(1H-indol-3-yl)propoxy]pyr...)
Affinity DataIC50: 3.67E+3nMAssay Description:The kinase assay uses His-Akt1 and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidin-coated FLASH plat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2007
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM15058(N-(3-{5-[(2S)-2-amino-3-(1H-indol-3-yl)propoxy]pyr...)
Affinity DataIC50: 3.67E+3nMAssay Description:Inhibition of AktMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed