BDBM150235 US8980929, Example Compound 3

SMILES N[C@H]1C[C@H](CCO[C@@H]1c1cc(F)ccc1F)N1Cc2cnn(c2C1)-c1ccccc1

InChI Key InChIKey=HYYNKMBJAHIQSY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 150235   

TargetDipeptidyl peptidase 4(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM150235(US8980929, Example Compound 3)
Affinity DataIC50: 3nMpH: 7.5Assay Description:A continuous fluorometric assay is employed with the substrate Gly-Pro-AMC, which is cleaved by DPP-4 to release the fluorescent AMC leaving group. T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/10/2015
Entry Details
Go to US Patent