BDBM150167 US8980887, Compound 10

SMILES CCN(Cc1ccncc1)C(=O)Cc1c(nc2cc(C)ccn12)-c1ccc(Cl)c(Cl)c1

InChI Key InChIKey=WXCBACASSXWEFP-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 150167   

TargetTranslocator protein(Rat)
Toxicology Academy of Military Medical Sciences P.L.A.

US Patent
LigandPNGBDBM150167(US8980887, Compound 10)
Affinity DataKi:  11.1nM ΔG°:  -11.0kcal/mole IC50: 26.1nMT: 2°CAssay Description:Competitive Binding Test of Drug to the Receptor (Rat Heart TSPO) and Radioligand (3H-PK11195): (1) tubes were placed in reaction condition of 30 C.(...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/10/2015
Entry Details
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