BDBM15015 2-tert-Butyl 4-Ethyl 3-Ethyl-5-formyl-1H-pyrrole-2,4-dicarboxylate::Pyrrole Analogue 5

SMILES CCOC(=O)c1c(CC)c([nH]c1C=O)C(=O)OC(C)(C)C

InChI Key InChIKey=BNPQXRAHFOXOEJ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 15015   

TargetInsulin receptor(Human)
Merck Research Laboratories

LigandPNGBDBM15015(2-tert-Butyl 4-Ethyl 3-Ethyl-5-formyl-1H-pyrrole-2...)
Affinity DataIC50: 2.00E+3nMpH: 7.4 T: 2°CAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate.HTRF is based on the proximity of europium cryptate (donor fluorophore...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2007
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Merck Research Laboratories

LigandPNGBDBM15015(2-tert-Butyl 4-Ethyl 3-Ethyl-5-formyl-1H-pyrrole-2...)
Affinity DataIC50: 490nMpH: 7.4 T: 2°CAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate.HTRF is based on the proximity of europium cryptate (donor fluorophore...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2007
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Merck Research Laboratories

LigandPNGBDBM15015(2-tert-Butyl 4-Ethyl 3-Ethyl-5-formyl-1H-pyrrole-2...)
Affinity DataIC50: 490nMAssay Description:Inhibition of IGF-1RMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed