BDBM149902 US8975415, RP183::US9242973, RP183
SMILES CC1(C)Oc2ccc(cc2C2(COC(N)=N2)C11COC1)-c1cccc(OC(F)(F)F)c1
InChI Key InChIKey=QIAHDRDUKXPIPE-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 149902
Affinity DataIC50: 1.08E+3nMAssay Description:Potency of test compounds were determined by measurement of their inhibition of BACE1 activity toward a fluorescent substrate. Experiments were perfo...More data for this Ligand-Target Pair
Affinity DataIC50: 880nMAssay Description:Potency of compounds were also measured using another fluorogenic substrate, TruPoint BACE1 Substrate Eu-CEVNLDAEFK-QSY 7 (SEQ ID NO:3) (AD0258, Perk...More data for this Ligand-Target Pair
Affinity DataIC50: 1.08E+3nMpH: 4.4 T: 2°CAssay Description:Test Example 1: Potency of test compounds were determined by measurement of their inhibition of BACE1 activity toward a fluorescent substrate. Experi...More data for this Ligand-Target Pair
Affinity DataIC50: 880nMAssay Description:Test Example 2: Potency of compounds were also measured using another fluorogenic substrate, TruPoint BACE1 Substrate Eu-CEVNLDAEFK-QSY 7 (SEQ ID NO:...More data for this Ligand-Target Pair