BDBM149886 US8975415, RP167::US9242973, RP167

SMILES CCC\C=C\c1ccc2OC(C)(C)C3(COC3)C3(COC(N)=N3)c2c1

InChI Key InChIKey=DKGSWKREOJWJTP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 149886   

TargetBeta-secretase 1(Human)
Comentis

US Patent
LigandPNGBDBM149886(US8975415, RP167 | US9242973, RP167)
Affinity DataIC50: 869nMAssay Description:Potency of test compounds were determined by measurement of their inhibition of BACE1 activity toward a fluorescent substrate. Experiments were perfo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/10/2015
Entry Details
Go to US Patent

TargetBeta-secretase 1(Human)
Comentis

US Patent
LigandPNGBDBM149886(US8975415, RP167 | US9242973, RP167)
Affinity DataIC50: 869nMpH: 4.4 T: 2°CAssay Description:Test Example 1: Potency of test compounds were determined by measurement of their inhibition of BACE1 activity toward a fluorescent substrate. Experi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2016
Entry Details
Go to US Patent