BDBM149879 US8975415, RP160::US9242973, RP160

SMILES CC1(C)Oc2ccc(cc2C2(COC(N)=N2)C11COC1)-c1cncc(c1)C#N

InChI Key InChIKey=LXZVBTDOKAHNDX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 149879   

TargetBeta-secretase 1(Human)
Comentis

US Patent
LigandPNGBDBM149879(US8975415, RP160 | US9242973, RP160)
Affinity DataIC50: 981nMAssay Description:Potency of test compounds were determined by measurement of their inhibition of BACE1 activity toward a fluorescent substrate. Experiments were perfo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/10/2015
Entry Details
Go to US Patent

TargetBeta-secretase 1(Human)
Comentis

US Patent
LigandPNGBDBM149879(US8975415, RP160 | US9242973, RP160)
Affinity DataIC50: 981nMpH: 4.4 T: 2°CAssay Description:Test Example 1: Potency of test compounds were determined by measurement of their inhibition of BACE1 activity toward a fluorescent substrate. Experi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2016
Entry Details
Go to US Patent