BDBM14956 5-(2-(2-Aminopyrimidin-5-yl)ethynyl)-2-methoxy-N-(2-(piperidin-1-yl)-5-(trifluoromethyl)phenyl)benzamide::5-[2-(2-aminopyrimidin-5-yl)ethynyl]-2-methoxy-N-[2-(piperidin-1-yl)-5-(trifluoromethyl)phenyl]benzamide::alkynylpyrimidine amide 6g

SMILES COc1ccc(cc1C(=O)Nc1cc(ccc1N1CCCCC1)C(F)(F)F)C#Cc1cnc(N)nc1

InChI Key InChIKey=RRZDLEADQGXQKI-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 14956   

TargetAngiopoietin-1 receptor(Human)
Amgen

LigandPNGBDBM14956(5-(2-(2-Aminopyrimidin-5-yl)ethynyl)-2-methoxy-N-(...)
Affinity DataIC50: 21nMpH: 7.5 T: 2°CAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2007
Entry Details Article
PubMed
LigandPNGBDBM14956(5-(2-(2-Aminopyrimidin-5-yl)ethynyl)-2-methoxy-N-(...)
Affinity DataIC50: 390nMAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2007
Entry Details Article
PubMed
LigandPNGBDBM14956(5-(2-(2-Aminopyrimidin-5-yl)ethynyl)-2-methoxy-N-(...)
Affinity DataIC50: 2.50E+4nMAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2007
Entry Details Article
PubMed