BDBM149474 US8975260, 121

SMILES CN1CCn2nc(Nc3cc(n[nH]c3=O)-c3cccc(N4Cc5cc(sc5C4=O)C(C)(C)C)c3CO)cc2C1

InChI Key InChIKey=PBIGUDXXZKZSMW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 149474   

TargetTyrosine-protein kinase BTK(Human)
Genetech

US Patent
LigandPNGBDBM149474(US8975260, 121)
Affinity DataIC50: 48nMpH: 7.5Assay Description:A generalized procedure for a standard biochemical Btk Kinase Assay that can be used to test Formula I compounds is as follows. A master mix minus Bt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/3/2015
Entry Details
Go to US Patent