BDBM149473 US8975260, 120

SMILES CN1CCn2nc(Nc3cc(nn(C)c3=O)-c3cccc(N4Cc5cc(sc5C4=O)C(C)(C)C)c3CO)cc2C1

InChI Key InChIKey=VZDDUZAFBGBYFG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 149473   

TargetTyrosine-protein kinase BTK(Human)
Genetech

US Patent
LigandPNGBDBM149473(US8975260, 120)
Affinity DataIC50: 55nMpH: 7.5Assay Description:A generalized procedure for a standard biochemical Btk Kinase Assay that can be used to test Formula I compounds is as follows. A master mix minus Bt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/3/2015
Entry Details
Go to US Patent