BDBM149472 US8975260, 119

SMILES Cc1c(cccc1-c1cc(Nc2cc(CN3CC(F)(F)C3)n(C)n2)c(=O)[nH]n1)N1Cc2cc(sc2C1=O)C(C)(C)C

InChI Key InChIKey=FXWCPRZBMYBHJX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 149472   

TargetTyrosine-protein kinase BTK(Human)
Genetech

US Patent
LigandPNGBDBM149472(US8975260, 119)
Affinity DataIC50: 5nMpH: 7.5Assay Description:A generalized procedure for a standard biochemical Btk Kinase Assay that can be used to test Formula I compounds is as follows. A master mix minus Bt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/3/2015
Entry Details
Go to US Patent