BDBM149373 US8962860, 40

SMILES Clc1ccc(cc1)C1N(C(=O)NC1=S)c1ccc2[nH]cnc2c1

InChI Key InChIKey=XPTXSMOWEGMJQC-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 149373   

TargetGlutaminyl-peptide cyclotransferase(Human)
Probiodrug

US Patent
LigandPNGBDBM149373(US8962860, 40)
Affinity DataKi:  45.9nM ΔG°:  -10.2kcal/mole IC50: 256nMT: 2°CAssay Description:This novel assay was used to determine the kinetic parameters for most of the QC substrates. QC activity was analyzed spectrophotometrically using a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/3/2015
Entry Details
US Patent