BDBM149346 US8962859, 11

SMILES COc1cc(F)c2Oc3ccc(cc3C3(N=C(N)n4ccnc34)c2c1)-c1cccnc1F

InChI Key InChIKey=VNEGKSKZUFSXDG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 149346   

TargetBeta-secretase 1(Human)
Amgen

US Patent
LigandPNGBDBM149346(US8962859, 11)
Affinity DataIC50: 9nMpH: 4.2Assay Description:The assay buffer used in this screen is 0.05 M acetate, pH 4.2, 10% DMSO final, 100 uM genapol (which is a nonionic detergent, below its Critical Mic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2015
Entry Details
Go to US Patent