BDBM149273 US8962674, CU279

SMILES COc1cc(\C=C\C(=O)CC(=O)\C=C\c2c(O)cccc2OC)ccc1O

InChI Key InChIKey=IKVGHBBJEXRQMQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 149273   

TargetBeta-secretase 1(Human)
Tokyo Institute of Technology

US Patent
LigandPNGBDBM149273(US8962674, CU279)
Affinity DataIC50: 1.40E+3nMpH: 4.5 T: 2°CAssay Description:Compounds were dissolved in dimethylsulfoxide (DMSO), and further diluted in 0.1 M sodium acetate buffer (with 150 mM sodium chloride, pH 4.5). The s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2015
Entry Details
Go to US Patent

TargetMicrotubule-associated protein tau(Human)
Doshisha University

Curated by ChEMBL
LigandPNGBDBM149273(US8962674, CU279)
Affinity DataIC50: 910nMAssay Description:Inhibition of recombinant human TAU three-repeat microtubule-binding domain aggregation expressed in Escherichia coli after 16 hrs by thioflavin T fl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2018
Entry Details Article
PubMed