BDBM149270 US8962674, CU256

SMILES COc1ccc(\C=C\C(=O)CC(=O)\C=C\c2ccc(O)c(OC)c2)c(O)c1

InChI Key InChIKey=MGCSSXJISHHDFW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 149270   

TargetBeta-secretase 1(Human)
Tokyo Institute of Technology

US Patent
LigandPNGBDBM149270(US8962674, CU256)
Affinity DataIC50: 1.20E+3nMpH: 4.5 T: 2°CAssay Description:Compounds were dissolved in dimethylsulfoxide (DMSO), and further diluted in 0.1 M sodium acetate buffer (with 150 mM sodium chloride, pH 4.5). The s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2015
Entry Details
Go to US Patent

TargetMicrotubule-associated protein tau(Human)
Doshisha University

Curated by ChEMBL
LigandPNGBDBM149270(US8962674, CU256)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of recombinant human TAU three-repeat microtubule-binding domain aggregation expressed in Escherichia coli after 16 hrs by thioflavin T fl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2018
Entry Details Article
PubMed