BDBM148350 US8962637, 189::US8962637, 75

SMILES CN1CCN(CC1)C(=O)c1ccc(Nc2ncc3C(=O)N(CCc3n2)c2cc(NC(=O)c3cccc(c3)C(F)(F)F)ccc2C)cc1

InChI Key InChIKey=VVYZASSDHSWENI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 148350   

TargetProto-oncogene tyrosine-protein kinase Src(Human)
Debiopharm

US Patent
LigandPNGBDBM148350(US8962637, 189 | US8962637, 75)
Affinity DataIC50: 19nMAssay Description:Compounds were screened in the TR-FRET assay for JAK2 and c-Src kinase inhibition. Ultra light poly GT (Perkin Elmer) was used as the substrate for J...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2015
Entry Details
Go to US Patent