BDBM148238 US8962630, 47

SMILES CN(C)C1CCN(CC1)c1ccc(Nc2ncc3cc(C#N)n(C4CCCC4)c3n2)nc1

InChI Key InChIKey=GYNZGXINUJMHPX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 148238   

TargetCyclin-dependent kinase 1(Human)
Novartis

US Patent
LigandPNGBDBM148238(US8962630, 47)
Affinity DataIC50: 2.60E+3nMT: 2°CAssay Description:A 384-well microtiter IMAP-FPT (Molecular Devices Trade Mark Technology) endpoint assay was used for CDK1/cyclin B kinase activity measurements. The ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2015
Entry Details
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TargetCyclin-dependent kinase 2(Human)
Novartis

US Patent
LigandPNGBDBM148238(US8962630, 47)
Affinity DataIC50: 8.30E+3nMAssay Description:The assay was run under the conditions identical to that for CDK1/cyclin B except 0.25 nM CDK1/cyclin B was replaced with 0.3 nM CDK2/cyclin A. A 384...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2015
Entry Details
Go to US Patent