BDBM148136 US8962609, DMX-77

SMILES CN1CCC(CC1)Nc1ccc(Nc2nccc(n2)-c2ccc(N3CC[C@@H](F)C3)c(c2)C#N)cn1

InChI Key InChIKey=AYVFJLIIZPMLDY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 148136   

LigandPNGBDBM148136(US8962609, DMX-77)
Affinity DataIC50: 30nMpH: 7.5Assay Description:Inhibitions studies were performed using a time-resolved fluorescence-based Lanthascreen assay. Phosphorylation of a fluorescein-labelled substrate p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/15/2015
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase TBK1(Human)
Domainex

US Patent
LigandPNGBDBM148136(US8962609, DMX-77)
Affinity DataIC50: 30nMpH: 7.5Assay Description:Inhibitions studies were performed using a time-resolved fluorescence-based Lanthascreen assay. Phosphorylation of a fluorescein-labelled substrate p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/15/2015
Entry Details
Go to US Patent