BDBM148130 US8962609, DMX-71

SMILES COC[C@H]1CCCN1c1ccc(cc1C#N)-c1ccnc(Nc2ccc(NC(C)=O)nc2)n1

InChI Key InChIKey=NWLDIIJVPIJBAB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 148130   

LigandPNGBDBM148130(US8962609, DMX-71)
Affinity DataIC50: 30nMpH: 7.5Assay Description:Inhibitions studies were performed using a time-resolved fluorescence-based Lanthascreen assay. Phosphorylation of a fluorescein-labelled substrate p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/15/2015
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase TBK1(Human)
Domainex

US Patent
LigandPNGBDBM148130(US8962609, DMX-71)
Affinity DataIC50: 30nMpH: 7.5Assay Description:Inhibitions studies were performed using a time-resolved fluorescence-based Lanthascreen assay. Phosphorylation of a fluorescein-labelled substrate p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/15/2015
Entry Details
Go to US Patent