BDBM14809 N-(5,6-Diphenyl-furo[2,3-d]pyrimidin-4-yl)-benzamide::N-{5,6-diphenylfuro[2,3-d]pyrimidin-4-yl}benzamide::furanopyrimidine compound 11

SMILES O=C(Nc1ncnc2oc(c(-c3ccccc3)c12)-c1ccccc1)c1ccccc1

InChI Key InChIKey=PZRIDLMMMAFYQY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 14809   

TargetSerine/threonine-protein kinase Chk1(Human)
Vernalis (R&D)

LigandPNGBDBM14809(N-(5,6-Diphenyl-furo[2,3-d]pyrimidin-4-yl)-benzami...)
Affinity DataIC50: 1.00E+5nMpH: 7.5 T: 2°CAssay Description:Chk1 kinase activity was assayed in reaction buffer containing substrate peptide, enzyme, and inhibitor in the presence of 100uM ATP/[gamma-33P] ATP....More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2007
Entry Details Article
PubMed