BDBM148083 US8962609, DMX-17

SMILES O=C1CCc2ccc(Nc3nccc(n3)-c3ccc(N4CCCC4)c(c3)C#N)cc2N1

InChI Key InChIKey=LERPKMSQPRBRIA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 148083   

TargetSerine/threonine-protein kinase TBK1(Human)
Domainex

US Patent
LigandPNGBDBM148083(US8962609, DMX-17)
Affinity DataIC50: 30nMpH: 7.5Assay Description:Inhibitions studies were performed using a time-resolved fluorescence-based Lanthascreen assay. Phosphorylation of a fluorescein-labelled substrate p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/15/2015
Entry Details
Go to US Patent

LigandPNGBDBM148083(US8962609, DMX-17)
Affinity DataIC50: 30nMpH: 7.5Assay Description:Inhibitions studies were performed using a time-resolved fluorescence-based Lanthascreen assay. Phosphorylation of a fluorescein-labelled substrate p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/15/2015
Entry Details
Go to US Patent