BDBM14763 (R)-6,7-Dimethoxy-4-[3-(7-methoxy-naphthalen-2-yloxy)-pyrrolidin-1-yl]-quinazoline::6,7-Dimethoxy-4-pyrrolidylquinazoline 24::6,7-dimethoxy-4-[(3R)-3-[(7-methoxynaphthalen-2-yl)oxy]pyrrolidin-1-yl]quinazoline

SMILES COc1ccc2ccc(O[C@@H]3CCN(C3)c3ncnc4cc(OC)c(OC)cc34)cc2c1

InChI Key InChIKey=YCWMLVXTEBFVHL-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 14763   

LigandPNGBDBM14763((R)-6,7-Dimethoxy-4-[3-(7-methoxy-naphthalen-2-ylo...)
Affinity DataKi:  17nMAssay Description:PDE activity was monitored by measuring the hydrolysis of [3H]-cAMP to [3H]-AMP using a scintillation proximity assay (SPA). [3H]-AMP was captured by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2007
Entry Details Article
PubMed
LigandPNGBDBM14763((R)-6,7-Dimethoxy-4-[3-(7-methoxy-naphthalen-2-ylo...)
Affinity DataKi:  17nMAssay Description:Inhibition of PDE10AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
LigandPNGBDBM14763((R)-6,7-Dimethoxy-4-[3-(7-methoxy-naphthalen-2-ylo...)
Affinity DataKi:  273nMAssay Description:PDE activity was monitored by measuring the hydrolysis of [3H]-cAMP to [3H]-AMP using a scintillation proximity assay (SPA). [3H]-AMP was captured by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2007
Entry Details Article
PubMed
LigandPNGBDBM14763((R)-6,7-Dimethoxy-4-[3-(7-methoxy-naphthalen-2-ylo...)
Affinity DataKi:  273nMAssay Description:Inhibition of PDE3AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B(Human)
St. John'S University

Curated by ChEMBL
LigandPNGBDBM14763((R)-6,7-Dimethoxy-4-[3-(7-methoxy-naphthalen-2-ylo...)
Affinity DataKi:  305nMAssay Description:Inhibition of PDE3BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed