BDBM14761 (R)-6,7-Dimethoxy-4-[3-(naphthalen-1-yloxy)-pyrrolidin-1-yl]-quinazoline::6,7-Dimethoxy-4-pyrrolidylquinazoline 22::6,7-dimethoxy-4-[(3R)-3-(naphthalen-1-yloxy)pyrrolidin-1-yl]quinazoline

SMILES COc1cc2ncnc(N3CC[C@H](C3)Oc3cccc4ccccc34)c2cc1OC

InChI Key InChIKey=PLHMFMNGOAPGBB-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 14761   

LigandPNGBDBM14761(6,7-dimethoxy-4-[(3R)-3-(naphthalen-1-yloxy)pyrrol...)
Affinity DataKi:  48nMAssay Description:PDE activity was monitored by measuring the hydrolysis of [3H]-cAMP to [3H]-AMP using a scintillation proximity assay (SPA). [3H]-AMP was captured by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2007
Entry Details Article
PubMed
LigandPNGBDBM14761(6,7-dimethoxy-4-[(3R)-3-(naphthalen-1-yloxy)pyrrol...)
Affinity DataKi:  48nMAssay Description:Inhibition of PDE3AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
LigandPNGBDBM14761(6,7-dimethoxy-4-[(3R)-3-(naphthalen-1-yloxy)pyrrol...)
Affinity DataKi:  56nMAssay Description:PDE activity was monitored by measuring the hydrolysis of [3H]-cAMP to [3H]-AMP using a scintillation proximity assay (SPA). [3H]-AMP was captured by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2007
Entry Details Article
PubMed
LigandPNGBDBM14761(6,7-dimethoxy-4-[(3R)-3-(naphthalen-1-yloxy)pyrrol...)
Affinity DataKi:  56nMAssay Description:Inhibition of PDE3BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
LigandPNGBDBM14761(6,7-dimethoxy-4-[(3R)-3-(naphthalen-1-yloxy)pyrrol...)
Affinity DataKi:  210nMAssay Description:PDE activity was monitored by measuring the hydrolysis of [3H]-cAMP to [3H]-AMP using a scintillation proximity assay (SPA). [3H]-AMP was captured by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2007
Entry Details Article
PubMed
LigandPNGBDBM14761(6,7-dimethoxy-4-[(3R)-3-(naphthalen-1-yloxy)pyrrol...)
Affinity DataKi:  2.08E+8nMAssay Description:Inhibition of PDE10AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed