BDBM147463 US8957103, D

SMILES COc1cc(cc(OC)c1OC)C1=C(C(=O)NC1=O)c1cn(CCOC(=O)C(N)CC(C)C)c2ccccc12

InChI Key InChIKey=ZKLYZABPCRFWBD-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 147463   

TargetVascular endothelial growth factor receptor 2(Human)
Johannes Gutenberg—Universitat Mainz

US Patent
LigandPNGBDBM147463(US8957103, D)
Affinity DataIC50: 251nMAssay Description:The effect of test compounds on the activity of the protein kinases GSK-3β, VEGFR-2 and FLT-3 was evaluated based on half maximal inhibitory con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/15/2015
Entry Details
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TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Johannes Gutenberg—Universitat Mainz

US Patent
LigandPNGBDBM147463(US8957103, D)
Affinity DataIC50: 239nMAssay Description:The effect of test compounds on the activity of the protein kinases GSK-3β, VEGFR-2 and FLT-3 was evaluated based on half maximal inhibitory con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/15/2015
Entry Details
Go to US Patent

TargetGlycogen synthase kinase-3 beta(Human)
Johannes Gutenberg—Universitat Mainz

US Patent
LigandPNGBDBM147463(US8957103, D)
Affinity DataIC50: 12nMAssay Description:The effect of test compounds on the activity of the protein kinases GSK-3β, VEGFR-2 and FLT-3 was evaluated based on half maximal inhibitory con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/15/2015
Entry Details
Go to US Patent