BDBM147263 US8957093, 83

SMILES Cc1c(C)c2cc(ccc2n1Cc1ccc(cc1)-c1ccccc1C(O)=O)C(=O)NCc1cccs1

InChI Key InChIKey=IHHFNXUOISFOGV-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 147263   

TargetPeroxisome proliferator-activated receptor gamma(Human)
The Scripps Research Institute

US Patent
LigandPNGBDBM147263(US8957093, 83)
Affinity DataIC50: 1nMAssay Description:The assay was performed according to manufacturer protocol. A mixture of nM GST-PPARG-LBD, 5 nM Tb-GST-antibody, 5 nM Fluormone Pan-PPAR Green, and s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/15/2015
Entry Details
Go to US Patent

TargetPeroxisome proliferator-activated receptor gamma(Human)
The Scripps Research Institute

US Patent
LigandPNGBDBM147263(US8957093, 83)
Affinity DataIC50: 1nMAssay Description:Binding affinity to GST-tagged PPAR-gamma-LBD (unknown origin) after 2 hrs by Lantha screen assay using fluormone Pan-PPAR green probeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
The Scripps Research Institute

US Patent
LigandPNGBDBM147263(US8957093, 83)
Affinity DataEC50:  196nMAssay Description:Transactivation of human PPARgamma in HEK293T cells after 18 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed