BDBM147179 US8957083, 21

SMILES CN1C(=N)NC2(CC1=O)c1cc(ccc1Oc1cnc(cc21)-c1cccnc1F)-c1cccnc1F

InChI Key InChIKey=IXOOHWPMALLLJD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 147179   

TargetBeta-secretase 1(Human)
Amgen

US Patent
LigandPNGBDBM147179(US8957083, 21)
Affinity DataIC50: 48.3nMpH: 4.2Assay Description:The assay buffer used in this screen is 0.05 M acetate, pH 4.2, 10% DMSO final, 100 uM genapol (which is a nonionic detergent, below its Critical Mic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2015
Entry Details
Go to US Patent