BDBM147172 US8957083, 21- A

SMILES CN1C(=O)C[C@@]2(N=C1N)c1cc(ccc1Oc1cnc(cc21)-c1ccnc(F)c1)-c1cccnc1F

InChI Key InChIKey=VHTKTKZPDQNTQN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 147172   

TargetBeta-secretase 1(Human)
Amgen

US Patent
LigandPNGBDBM147172(US8957083, 21- A)
Affinity DataIC50: 437nMpH: 4.2Assay Description:The assay buffer used in this screen is 0.05 M acetate, pH 4.2, 10% DMSO final, 100 uM genapol (which is a nonionic detergent, below its Critical Mic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2015
Entry Details
Go to US Patent