BDBM147161 US8957083, 35

SMILES CN1C(N)=N[C@]2(C1=O)c1cc(ccc1Oc1c(F)cc(cc21)C1=CCOCC1)-c1cccc(Cl)c1

InChI Key InChIKey=KEMWQNNZCODMGI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 147161   

TargetBeta-secretase 1(Human)
Amgen

US Patent
LigandPNGBDBM147161(US8957083, 35)
Affinity DataIC50: 24.3nMpH: 4.2Assay Description:The assay buffer used in this screen is 0.05 M acetate, pH 4.2, 10% DMSO final, 100 uM genapol (which is a nonionic detergent, below its Critical Mic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2015
Entry Details
Go to US Patent