BDBM147155 US8957083, 31

SMILES CC#Cc1cncc(c1)-c1ccc2Oc3c(F)cc(cc3[C@]3(N=C(N)N(C)C3=O)c2c1)C1=CCOCC1

InChI Key InChIKey=LFHRVTJUXIOETI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 147155   

TargetBeta-secretase 1(Human)
Amgen

US Patent
LigandPNGBDBM147155(US8957083, 31)
Affinity DataIC50: 179nMpH: 4.2Assay Description:The assay buffer used in this screen is 0.05 M acetate, pH 4.2, 10% DMSO final, 100 uM genapol (which is a nonionic detergent, below its Critical Mic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2015
Entry Details
Go to US Patent