BDBM147135 US8957077, L-4

SMILES C(Nc1cc(OC[C@H]2C[C@@H]2c2ccccn2)nc2ccnn12)c1cn[nH]c1

InChI Key InChIKey=ZFWAJANXDQOOAB-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 147135   

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM147135(US8957077, L-4)
Affinity DataKi:  0.240nMAssay Description:In a typical experiment the PDE10 inhibitory activity of the compounds of the present invention was determined in accordance with the following exper...More data for this Ligand-Target Pair
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Date in BDB:
7/10/2015
Entry Details
Go to US Patent