BDBM146690 US8957073, 4.24::US9718803, 4.24

SMILES COc1cc(cc(c1)C(F)(F)F)-c1nccnc1C1CN(C1)c1ccc2ccccc2n1

InChI Key InChIKey=DHGSOPWKJRYKIC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 146690   

LigandPNGBDBM146690(US8957073, 4.24 | US9718803, 4.24)
Affinity DataIC50: 0.0149nMT: 2°CAssay Description:Enzyme Activity. An IMAP TR-FRET assay was used to analyze the enzyme activity (Molecular Devices Corp., Sunnyvale Calif.). 5 uL of serial diluted PD...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2015
Entry Details
Go to US Patent

LigandPNGBDBM146690(US8957073, 4.24 | US9718803, 4.24)
Affinity DataIC50: 0.0150nMT: 2°CAssay Description:An IMAP TR-FRET assay was used to analyze the enzyme activity (Molecular Devices Corp., Sunnyvale Calif.). 5 L of serial diluted PDE10A (BPS Bioscien...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2018
Entry Details
Go to US Patent